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pentobarbital will decrease the extent or influence of tofacitinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. Loss of, or reduced reaction to tofacitinib may possibly arise when coadministered with powerful CYP3A4 inducersMinor (1)pentobarbital will decrease the level or impact of paclitaxel protein sure by influ